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Learning Counterfactual Representations for Estimating Individual Dose-Response Curves

Estimating what would be an individual's potential response to varying levels of exposure to a treatment is of high practical relevance for several important fields, such as healthcare, economics and public policy. However, existing methods for learning to estimate counterfactual outcomes from observational data are either focused on estimating average dose-response curves, or limited to settings with only two treatments that do not have an associated dosage parameter. Here, we present a novel machine-learning approach towards learning counterfactual representations for...

Instance Segmentation for the Quantification of Microplastic Fiber Images

Microplastics pollution has been recognized as a serious environmental concern, with research efforts underway to determine primary causes. Experiments typically generate bright-field images of microplastic fibers that are filtered from water. Environmental decision making in process engineering critically relies on accurate quantification of mi-croplastic fibers in these images. To satisfy the required standards, images are often analyzed manually, resulting in a highly tedious process, with thousands of fiber instances per image. While the shape of individual fibers is relatively simple,...

From Sets to Multisets: Provable Variational Inference for Probabilistic Integer Submodular Models

DeepHeartBeat: Latent trajectory learning of cardiac cycles using cardiac ultrasounds

Echocardiography monitors the heart movement for noninvasive diagnosis of heart diseases. It proves to be of profound practical importance as it combines low-cost portable instrumentation and rapid image acquisition without the risks of ionizing radiation. However, echocardiograms produce high-dimensional, noisy data which frequently proved difficult to interpret. As a solution, we propose a novel autoencoder-based framework, DeepHeartBeat, to learn human interpretable representations of cardiac cycles from cardiac ultrasound data. Our model encodes high dimensional observations by a cyclic trajectory in...

Continuous submodular function maximization

Continuous submodular functions are a category of generally non-convex/non-concave functions with a wide spectrum of applications. The celebrated property of this class of functions - continuous submodularity - enables both exact minimization and approximate maximization in poly. time. Continuous submodularity is obtained by generalizing the notion of submodularity from discrete domains to continuous domains. It intuitively captures a repulsive effect amongst different dimensions of the defined multivariate function. In this paper, we systematically study continuous submodularity and a class of...

Artificial intelligence in echocardiography diagnostics – detection of takotsubo syndrome

Unsupervised Mitral Valve Segmentation in Echocardiography with Neural Network Matrix Factorization

SPINDLE: End-to-end learning from EEG/EMG to extrapolate animal sleep scoring across experimental settings, labs and species

Understanding sleep and its perturbation by environment, mutation, or medication remains a central problem in biomedical research. Its examination in animal models rests on brain state analysis via classification of electroencephalographic (EEG) signatures. Traditionally, these states are classified by trained human experts by visual inspection of raw EEG recordings, which is a laborious task prone to inter-individual variability. Recently, machine learning approaches have been developed to automate this process, but their generalization capabilities are often insufficient, especially across animals from...

Optimal Continuous DR-Submodular Maximization and Applications to Provable Mean Field Inference

Learning Counterfactual Representations for Estimating Individual Dose-Response Curves-2019