We perform teaching and research in machine learning strategies for the pattern analysis of various kinds of data. This comprises statistical models for clustering, graphical models for network inference and algorithmic methods to efficiently find these structures in the data.
We perform teaching and research in machine learning strategies for the pattern analysis of various kinds of data. This comprises statistical models for clustering, graphical models for network inference and algorithmic methods to efficiently find these structures in the data.
Journal Article - page 4
Dissecting psychiatric spectrum disorders by generative embedding
This proof-of-concept study examines the feasibility of defining subgroups in psychiatric spectrum disorders by generative embedding, using dynamical system models which infer neuronal circuit mechanisms from neuroimaging data. To this end, we re-analysed an fMRI dataset of 41 patients diagnosed with schizophrenia and 42 healthy controls performing a numerical n-back working-memory task. In our generative-embedding approach, we used parameter estimates from a dynamic causal model (DCM) of a visual–parietal–prefrontal network to define a model-based feature space for the subsequent application...